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Luigi Ferrucci Selected Research

Chronic Disease (Chronic Diseases)

1/2022Getting closer to the clinic.
11/2020Plasma proteomic biomarker signature of age predicts health and life span.
1/2020Measuring biological aging in humans: A quest.
12/2019Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors.
12/2018A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.
1/2017Epigenetic clock analysis of diet, exercise, education, and lifestyle factors.
1/2017A double blind placebo controlled randomized trial of the effect of acute uric acid changes on inflammatory markers in humans: A pilot study.
1/2015Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers.
11/2014Trajectories of physiological dysregulation predicts mortality and health outcomes in a consistent manner across three populations.
7/2014Inflamm-aging does not simply reflect increases in pro-inflammatory markers.
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Luigi Ferrucci Research Topics

Disease

71Inflammation (Inflammations)
11/2022 - 04/2002
48Cardiovascular Diseases (Cardiovascular Disease)
11/2022 - 05/2003
45Chronic Disease (Chronic Diseases)
01/2022 - 05/2002
40Frailty
05/2022 - 06/2005
36Cognitive Dysfunction
01/2022 - 06/2004
36Peripheral Arterial Disease
11/2021 - 05/2004
35Neoplasms (Cancer)
10/2022 - 05/2003
35Alzheimer Disease (Alzheimer's Disease)
05/2022 - 07/2010
33Obesity
01/2021 - 08/2003
31Anemia
01/2022 - 08/2003
24Hypertension (High Blood Pressure)
01/2022 - 08/2003
23Dementia (Dementias)
01/2022 - 03/2005
23Sarcopenia
01/2022 - 08/2002
22Type 2 Diabetes Mellitus (MODY)
12/2021 - 12/2006
19Insulin Resistance
02/2019 - 07/2003
17Prostatic Neoplasms (Prostate Cancer)
10/2022 - 11/2006
16Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2020 - 12/2006
15Diabetes Mellitus
10/2022 - 08/2003
14Chronic Renal Insufficiency
01/2019 - 03/2007
12Coronary Disease (Coronary Heart Disease)
01/2019 - 06/2007
12Abdominal Obesity
01/2018 - 12/2006
11Stroke (Strokes)
12/2021 - 03/2005
10Atrophy
01/2020 - 07/2010
9Atherosclerosis
10/2022 - 08/2005
9Weight Loss (Weight Reduction)
01/2022 - 05/2003
8Heart Failure
01/2022 - 06/2003
8Coronary Artery Disease (Coronary Atherosclerosis)
05/2020 - 08/2010
6Hyperthyroidism
11/2021 - 11/2009
5Pressure Ulcer (Bedsore)
07/2022 - 01/2010
5Fatigue
05/2022 - 05/2010
5Myocardial Infarction
12/2021 - 11/2010
5Hypothyroidism
11/2021 - 11/2009
5Disease Progression
10/2021 - 07/2010
5Ischemia
01/2020 - 11/2010
5Thrombosis (Thrombus)
05/2011 - 08/2005
5Renal Insufficiency (Renal Failure)
01/2009 - 08/2003
4Macular Degeneration (Age-Related Maculopathy)
11/2022 - 05/2012
4Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 01/2018
4Ischemic Stroke
12/2021 - 10/2011

Drug/Important Bio-Agent (IBA)

48Biomarkers (Surrogate Marker)IBA
10/2022 - 11/2003
35Interleukin-6 (Interleukin 6)IBA
01/2020 - 03/2003
31Glucose (Dextrose)FDA LinkGeneric
01/2021 - 03/2004
26Biological ProductsIBA
11/2022 - 03/2004
25Proteins (Proteins, Gene)FDA Link
11/2022 - 10/2002
24C-Reactive ProteinIBA
01/2020 - 05/2003
22CholesterolIBA
01/2018 - 08/2003
20Hormones (Hormone)IBA
10/2022 - 05/2003
19Hemoglobins (Hemoglobin)IBA
10/2020 - 08/2003
19HDL CholesterolIBA
01/2019 - 08/2003
18Amyloid (Amyloid Fibrils)IBA
01/2022 - 09/2008
18Triglycerides (Triacylglycerol)IBA
01/2021 - 03/2004
17Testosterone (Sustanon)FDA Link
10/2022 - 01/2006
17LipidsIBA
01/2020 - 10/2004
17Advanced Glycation End ProductsIBA
04/2015 - 04/2007
16Insulin (Novolin)FDA Link
01/2021 - 03/2004
15IronIBA
11/2022 - 08/2003
15Vitamin DFDA LinkGeneric
01/2020 - 04/2007
14Pharmaceutical PreparationsIBA
11/2021 - 03/2004
13Apolipoproteins E (ApoE)IBA
11/2021 - 01/2011
13Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 03/2004
13Prostate-Specific Antigen (Semenogelase)IBA
12/2016 - 11/2006
12Carotenoids (Carotene)IBA
11/2022 - 01/2006
12Insulin-Like Growth Factor I (IGF-1)IBA
06/2022 - 03/2003
12Uric Acid (Urate)IBA
10/2019 - 05/2006
11ErythropoietinFDA Link
11/2015 - 08/2005
10hydroxide ionIBA
03/2017 - 05/2002
10AntioxidantsIBA
01/2017 - 01/2006
10LeptinIBA
02/2016 - 12/2006
925-hydroxyvitamin DIBA
10/2022 - 07/2010
9CytokinesIBA
01/2018 - 08/2005
8CreatinineIBA
04/2018 - 05/2004
8Folic Acid (Vitamin M)FDA LinkGeneric
07/2012 - 10/2004
8SeleniumIBA
07/2012 - 01/2006
8fibrin fragment D (D-dimer)IBA
05/2010 - 05/2004
7Insulin-Like PeptidesIBA
06/2022 - 10/2008
7Antihypertensive Agents (Antihypertensives)IBA
05/2022 - 01/2005
7Blood Proteins (Serum Proteins)IBA
01/2022 - 09/2006
7Peptides (Polypeptides)IBA
12/2021 - 03/2003
7Hydrocortisone (Cortisol)FDA LinkGeneric
01/2020 - 12/2006
7N(6)-carboxymethyllysine (carboxymethyllysine)IBA
04/2015 - 04/2007
6CalciumIBA
10/2022 - 07/2011
6Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2020 - 02/2004
6ApolipoproteinsIBA
12/2019 - 01/2011
6HomocysteineIBA
09/2013 - 08/2005
5ORALIT (ORS)IBA
10/2022 - 10/2009
5Thyroxine (Levothyroxine)FDA LinkGeneric
11/2021 - 05/2015
5Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
11/2021 - 09/2013
5LDL CholesterolIBA
01/2019 - 08/2003
5HDL LipoproteinsIBA
04/2015 - 08/2003
5Estradiol (Delestrogen)FDA LinkGeneric
01/2015 - 02/2009
5InterleukinsIBA
07/2014 - 12/2002
5Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
04/2014 - 03/2004
5Vitamin EFDA LinkGeneric
10/2012 - 02/2004
5AdiponectinIBA
01/2012 - 12/2009
5alpha-TocopherolFDA Link
12/2011 - 03/2006
4Parathyroid Hormone (Parathormone)IBA
10/2022 - 01/2009
4Sex Hormone-Binding GlobulinIBA
10/2022 - 12/2006
4Indicators and Reagents (Reagents)IBA
12/2021 - 11/2003

Therapy/Procedure

19Therapeutics
01/2022 - 04/2002
15Activities of Daily Living (ADL)
01/2019 - 05/2003